"Birth defects in children of men exposed in utero to diethylstilbestrol (DES)"; this is not COVID related but a critical study I wanted to share as to DES (diethylstilbestrol) & adverse effects
by Paul Alexander
Tournaire et al.: suggests an increased incidence of two male genital tract defects in sons of men prenatally exposed to DES, namely cryptorchidism and hypoplasia of the penis
“Results: An increased incidence of two genital anomalies, cryptorchidism (OR=5.72; 95% CI 1.51-21.71), and hypoplasia of the penis (OR=22.92; 95% CI 3.81-137.90), was observed in the 209 sons of prenatally exposed men compared with controls, but hypospadias incidence was not increased in comparison with either the controls or the general population. No increase of genital anomalies was observed in daughters.
Conclusion: …this work suggests an increased incidence of two male genital tract defects in sons of men prenatally exposed to DES. This transgenerational effect, already observed in animals and in the offspring of women prenatally exposed to DES, could be the result of epigenetic changes transmitted to the subsequent generation through men.”