BOOM! Natural immunity wins again!! A win for Team Natural! Mioch et al.: "SARS-CoV-2 antibodies persist up to 12 months after natural infection in healthy employees working in non-medical contact-

by Paul Alexander

-intensive professions"; SARS-CoV-2 antibodies persisted for up to one year after initial seropositivity, suggesting long-term natural immunity.

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Now to the study:

 

SOURCE:

https://pubmed.ncbi.nlm.nih.gov/36436751/

Researchers sought to ‘evaluate dynamics of antibody levels following exposure to SARS-CoV-2 during 12 months in Dutch non-vaccinated hairdressers and hospitality staff.’

A prospective cohort study design, ‘blood samples were collected every three months for one year, and analyzed using a qualitative total antibody ELISA and a quantitative IgG antibody ELISA.

Researchers found that 95 of 497 participants (19.1%) ‘had ≥1 seropositive measurement before their last visit using the qualitative ELISA. Only 2.1% (2/95) seroreverted during follow-up. Of the 95 participants, 82 (86.3%) tested IgG seropositive in the quantitative ELISA too. IgG antibody levels significantly decreased in the first months (p<0.01), but remained detectable up to 12 months in all participants. Higher age (B, 10-years increment: 24.6, 95%CI: 5.7-43.5) and higher BMI (B, 5kg/m² increment: 40.0, 95%CI: 2.9-77.2) were significantly associated with a higher peak of antibody levels.’

These results indicate that ‘SARS-CoV-2 antibodies persisted for up to one year after initial seropositivity, suggesting long-term natural immunity.’