BRADBURNE & TYRRELL in 1967, showed us while coronavirus 229E was just discovered 1966, 40% British adults & 30% children had antibodies collected prior 10 years before challenge; how? 10 yrs prior???

Challenged volunteers with the 229E prototype in 1966; showed us there were antibodies ALREADY existing in the population, where about 40% of adults possessed antibody as well as children

Thanks to good work by Jefferson and Heneghan.

For 10 years this was circulating and no one knew???? So could COVID-19 SARS-CoV-2 been circulating for a decade prior???? Maybe just after the 2015 publication by Baric???

SOURCE:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1843247/pdf/brmedj02154-0035.pdf

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