BRADBURNE & TYRRELL in 1967, showed us while coronavirus 229E was just discovered 1966, 40% British adults & 30% children had antibodies collected prior 10 years before challenge; how? 10 yrs prior???

by Paul Alexander

Challenged volunteers with the 229E prototype in 1966; showed us there were antibodies ALREADY existing in the population, where about 40% of adults possessed antibody as well as children

Thanks to good work by Jefferson and Heneghan.

For 10 years this was circulating and no one knew???? So could COVID-19 SARS-CoV-2 been circulating for a decade prior???? Maybe just after the 2015 publication by Baric???


Key passages: