CDC's and FDA's Bedford slides are fascinating & he titled it "Continuing SARS-CoV-2 evolution under population immune pressure"; he is WRONG, its NOT population pressure, it's non-neutralizing vax pressure
by Paul Alexander
These 3 pieces of information tells the story & I like his work here but his take on why immune escape is happening so fast is misguided; its the infectious pressure on top of sub-optimal vax pressure
We underestimate the evolutionary capacity of the virus to evolve and adapt to the ongoing infectious pressure on top of the mounting sub-optimal immune pressure driving selection of infectious variant after variant.
