Danis: Did Danis et al. early in 2020 in their French Alps chalet study of a cluster of COVID cases, show no secondary transmission from a pedicatric case (even after visiting 3 schools)? The fact
by Paul Alexander
that an infected child did not transmit the disease despite close interactions within schools suggested limited (near 0) transmission in children. Danis et al. showed us ealy children DID NOT spread
‘Background: On 7 February 2020, French Health authorities were informed of a confirmed case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an Englishman infected in Singapore who had recently stayed in a chalet in the French Alps.
Results: The index case stayed 4 days in the chalet with 10 English tourists and a family of 5 French residents; SARS-CoV-2 was detected in 5 individuals in France, 6 in England (including the index case), and 1 in Spain (overall attack rate in the chalet: 75%).
One pediatric case, with picornavirus and influenza A coinfection, visited 3 different schools while symptomatic.
One case was asymptomatic, with similar viral load as that of a symptomatic case. Seven days after the first cases were diagnosed, 1 tertiary case was detected in a symptomatic patient with from the chalet a positive endotracheal aspirate; all previous and concurrent nasopharyngeal specimens were negative. Additionally, 172 contacts were monitored; all contacts tested for SARS-CoV-2 (N = 73) were negative.
Conclusions: The occurrence in this cluster of 1 asymptomatic case with similar viral load as a symptomatic patient suggests transmission potential of asymptomatic individuals.
The fact that an infected child did not transmit the disease despite close interactions within schools suggests potential different transmission dynamics in children.’