Doctors (Marik): Evidence suggests that the combination of vitamin C, corticosteroids & thiamine acts synergistically to reverse sepsis (septic shock) induced organ dysfunction; intravenous vitamin C
by Paul Alexander
Intravenous (IV) vitamin C, thiamine, & hydrocortisone; Vit C protocol (Marik): Only 4 of 47 patients treated with the protocol did not survive (8.5%), while 19 of the 47 control patients died (40%)
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These findings are very applicable to sepsis in severely ill COVID patients.
‘After the first life-saving success, his vitamin C / hydrocortisone / thiamine protocol was used to treat 47 consecutive septic patients over seven months in 2016. He compared the results he achieved with these patients in a retrospective manner with a control group of septic patients treated without his new protocol during the prior seven months, simply looking at the outcome of survival.’
Dr. Marik's results were stunning. Only 4 of the 47 patients treated with the protocol did not survive (8.5%), while 19 of the 47 control patients (who did not receive this protocol) died (40.4%). None of the treated patients developed any organ failure, and all of the treated patients were able to be weaned off of vasopressors (blood pressure-supporting drugs) within roughly 24 hours of starting the protocol.
Treating sepsis with vitamin C, thiamine, and hydrocortisone: Exploring the quest for the magic elixir.Obi J, et al. J Crit Care. 2020. PMID: 32061462 Free PMC article. Review.
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.Marik PE, et al. Chest. 2017. PMID: 27940189
Metabolic support in sepsis: corticosteroids and vitamins: the why, the when, the how.Fujii T, et al. Curr Opin Crit Care. 2020. PMID: 32487845 Review.
Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial.Sevransky JE, et al. JAMA. 2021. PMID: 33620405 Free PMC article. Clinical Trial.
Emerging Adjunctive Approach for the Treatment of Sepsis: Vitamin C and Thiamine. Badeaux JE, et al. Crit Care Nurs Clin North Am. 2018. PMID: 30098738 Review.