Further failure of Pfizer mRNA COVID gene injection: Collier et al. "Immunogenicity of the BA.5 Bivalent mRNA Vaccine Boosters"; "data show that BA.5 NAb titers were comparable following monovalent &
by Paul Alexander
bivalent mRNA boosters." What does that mean? It means that the Pfizer bi-valent booster failed, AGAIN, and go ask Rochelle specifically how it failed her; Original antigenic sin (OAS) initial prime
Go ask Rochelle how well her 5th shot worked, the new bivalent booster studied here. Ask her how well it stops infection or transmission of the omicron BA4/BA5 sub-variant. What a bunch of bullshit, corrupted fraud health officials Walensky, Francis Collins, Fauci, Birx, all of them are and were! Murthy, Ashish Jha, Hahn, a bunch of stupid moronic health officials, should all be fired and include Howard Njoo and Theresa Tam out of Canada and the moron Juni of Ontario.
Investigate Trudeau and Doug Ford for read what I wrote here: based on all we know, there will be deaths of existing police and military in Canada and US who were mandated to take the fraud harmful vaccine. Under threat of law. Look what are doing with James Topp, veteran. We knew it, we told them to stop it and not mandate it. Many police and military in Canada will die in time. As sure as the sun will shine and due 100% to the COVID fraud vaccine. We told them to stop! I did!
The initial prime or exposure e.g. to the initial legacy Wuhan strain in the initial monovalent injection plays a potent role (OAS) (immune priming, immune fixation, immune imprinting, immune prejudicing). OAS can happen post natural infection or vaccination. But remember, with natural exposure infection, the immune response e.g. if using COVID virus as an example, is to the entire viral ball and spike, all the proteins and target antigens such as envelope, membrane, internal conserved nucleocapsid proteins etc. The COVID gene injection induces an immune response to ONLY the spike protein antigen (epitopes/binding sites).
The results show that the new bivalent booster injection (contains mRNA coding Wuhan spike + BA4/BA5 spike) confer no additional benefit compared to the initial mRNAs injections in targeting omicron. In short, the recalled antibody response is optimally to the initial Wuhan strain and not to the present omicron sub-variants.
“Our data demonstrate that both monovalent and bivalent mRNA boosters markedly increased antibody responses but did not substantially augment T cell responses. BA.5 NAb titers were comparable following monovalent and bivalent mRNA boosters, with a modest and nonsignificant trend favoring the bivalent booster by a factor of 1.3.”
This result is very troubling for it basically says it fails! We know that the antibodies wane rapidly yet with limited T lymphocyte response, this means limitation in capacity to clear out/eliminate virus to prevent severe illness.
Researchers ‘evaluated humoral and cellular immune responses in 15 individuals who received the original monovalent mRNA boosters and in 18 individuals who received the bivalent mRNA boosters’.
‘Our data demonstrate that both monovalent and bivalent mRNA boosters markedly increased antibody responses but did not substantially augment T cell responses. BA.5 NAb titers were comparable following monovalent and bivalent mRNA boosters’.
‘Findings suggest that immune imprinting by prior antigenic exposure5 may pose a greater challenge than currently appreciated for inducing robust immunity to SARS-CoV-2 variants.’
For example, “Spike-specific CD8+ and CD4+ T cell responses increased only modestly following monovalent and bivalent mRNA boosting. Median BA.5 CD8+ T cell responses increased from 0.027% to 0.048% following monovalent mRNA boosting and from 0.024% to 0.046% following bivalent mRNA boosting (Fig. 1C, 1D).”
“Median BA.5 CD4+ T cell responses increased from 0.060% to 0.130% following monovalent mRNA boosting and from 0.051% to 0.072% following bivalent mRNA boosting (Fig. 1E, 1F).”