Gill et al.'s profound case series on the autopsy histopathologic cardiac findings in 2 Adolescents (one in Connecticut and one in Michigan) Following the Second mRNA COVID-19 Vaccine Dose (Pfizer)
by Paul Alexander
The myocardial injury seen in these postvaccine hearts is different from typical myocarditis and has an appearance most closely resembling a catecholamine-mediated stress (toxic) cardiomyopathy.
SOURCE:
https://pubmed.ncbi.nlm.nih.gov/35157759/
For this series, Gill et al. report the autopsy ‘microscopic cardiac findings in adolescent deaths that occurred shortly following administration of the second Pfizer-BioNTech COVID-19 dose to determine if the myocarditis described in these instances has the typical histopathology of myocarditis.’
The design involved the ‘clinical and autopsy investigation of 2 teenage boys who died shortly following administration of the second Pfizer-BioNTech COVID-19 dose.’
Gill et al. report that the microscopic examination revealed features ‘resembling a catecholamine-induced injury, not typical myocarditis pathology.’
‘The myocardial injury seen in these postvaccine hearts is different from typical myocarditis and has an appearance most closely resembling a catecholamine-mediated stress (toxic) cardiomyopathy.
Understanding that these instances are different from typical myocarditis and that cytokine storm has a known feedback loop with catecholamines may help guide screening and therapy.’