Important I repost this map for us to look at again of Germany & COVID vax rates & omicron (BA.4/5); point is that in former East Germany (marked off with green line), much lower vaccination rates
by Paul Alexander
this meant the population of DDR developed high natural exposure immunity; remember also the vaccinated have greater infection due to non-neutralizing vaccinal antibodies as per evidence
We see that with elevated vaccine uptake in the western portion of Germany, the result. The portion of the nation that resisted the vaccine, with lower vaccine uptake, fared much better. Those nations with less vaccine will show less infection and we are seeing it in all the global data.
See South Africa COVID case map today below how it managed in the Omicron wave. It appears that there is this unholy alliance between Omicron and likely BA 4 and 5 clades (sub-variants) and level of vaccine. More vaccine, and high infectious pressure, means the vaccinal antibodies will bind to available spike but not neutralize, yet cause greater infection. Where there is less vaccine, even with high infectious pressure, there is is lower infection in the vaccinee…one of the two must be reduced, vaccine or infectious pressure. If not, we will have variant after variant because in simple terms, the COVID vaccine is not eliminating the virus. GVB also eloquently outlines this repeatedly.
This map below became marked and clear post December 2021 and the reasoning is that omicron is the culprit as it then dominated, and due to the non-neutralizing vaccinal antibodies, and high vaccine rates, the vaccinated is getting highly infected, more so than even for prior variants. Vaccinated persons in the era of BA.5 omicron, sees the vaccinal antibodies binding to the spike but not neutralizing it. The non-neutralizing (facilitating) antibodies via a process of antibody-dependent enhancement of infection (ADEI), actually facilitates and enhances infection in the vaccinee. Yahi et al. tells us this with prescient research:
“We show that enhancing antibodies reinforce the binding of the spike trimer to the host cell membrane by clamping the NTD to lipid raft microdomains. This stabilizing mechanism may facilitate the conformational change that induces the demasking of the receptor binding domain. As the NTD is also targeted by neutralizing antibodies, our data suggest that the balance between neutralizing and facilitating antibodies in vaccinated individuals is in favor of neutralization for the original Wuhan/D614G strain. However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity. Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors).”
This statement outlines clear original antigenic sin (OAS) (initial prime or imprinting prejudices all future immune response to the initial prime/exposure). Tells us the neutralizing antibodies do not bind but the non-neutralizing antibodies bind. It tells us that persons who get the current shot will be at risk and subject to ADEI as the vaccinal antibodies are to the Wuhan strain/spike but the antibodies confront omicron spike. How could it work?
And to assume that in the East more people are vaxxed etc. and this is why the east has lower rates is ludicrous. Where is the data to show this? I think Christian Drosten’s “ideal immunity” really is about drinking too much. Hey Chris, slow down on the bottle before you theorize this way, not with these fake, fraud, failed injections. That is wishful thinking.
see Eugyppius and a key statement:
“That’s right: The vaccines work so well, you need three doses, and then on top of that another three infections, to achieve this Drostenian “ideal immunity.” What fantastic magical elixirs these are.”