Is or was there early evidence of consistent pathophysiological alterations after vaccination with COVID-19 vaccines? Yes! We say not only for the Malone, Kariko, Weissman et al. mRNA technology based

gene injection but also DNA platforms, adeno-viral vector etc.; the issue is all of these vaccines end at some level with the spike protein & this is a catastrophic mess

SOURCE:

https://www.nature.com/articles/s41421-021-00329-3

‘Report, besides generation of neutralizing antibodies, consistent alterations in hemoglobin A1c, serum sodium and potassium levels, coagulation profiles, and renal functions in healthy volunteers after vaccination with an inactivated SARS-CoV-2 vaccine.

Similar changes had also been reported in COVID-19 patients, suggesting that vaccination mimicked an infection. Single-cell mRNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) before and 28 days after the first inoculation also revealed consistent alterations in gene expression of many different immune cell types. Reduction of CD8⁺ T cells and increase in classic monocyte contents were exemplary. Moreover, scRNA-seq revealed increased NF-κB signaling and reduced type I interferon responses, which were confirmed by biological assays and also had been reported to occur after SARS-CoV-2 infection with aggravating symptoms…

Study recommends additional caution when vaccinating people with pre-existing clinical conditions, including diabetes, electrolyte imbalances, renal dysfunction, and coagulation disorders.’