Is there a dose response whereby the Higher the Number of Vaccines Previously Received (mRNA technology based COVID gene injections), the Higher Risk of Contracting COVID? Shrestha et al. proved YES!

SOURCE:

https://academic.oup.com/ofid/article/10/6/ofad209/7131292

Shrestha et al.’s study included ‘employees of Cleveland Clinic in employment when the bivalent COVID-19 vaccine first became available.

Among 51 017 employees, COVID-19 occurred in 4424 (8.7%) during the study. In multivariable analysis, the bivalent-vaccinated state was associated with lower risk of COVID-19 during the BA.4/5-dominant (hazard ratio, 0.71 [95% confidence interval, .63–79]) and the BQ-dominant (0.80 [.69–.94]) phases, but decreased risk was not found during the XBB-dominant phase (0.96 [.82–.1.12]). The estimated vaccine effectiveness was 29% (95% confidence interval, 21%–37%), 20% (6%–31%), and 4% (−12% to 18%), during the BA.4/5-, BQ-, and XBB-dominant phases, respectively. The risk of COVID-19 also increased with time since the most recent prior COVID-19 episode and with the number of vaccine doses previously received.’