Is there a dose response whereby the Higher the Number of Vaccines Previously Received (mRNA technology based COVID gene injections), the Higher Risk of Contracting COVID? Shrestha et al. proved YES!
by Paul Alexander
Shrestha et al.’s study included ‘employees of Cleveland Clinic in employment when the bivalent COVID-19 vaccine first became available.
Among 51 017 employees, COVID-19 occurred in 4424 (8.7%) during the study. In multivariable analysis, the bivalent-vaccinated state was associated with lower risk of COVID-19 during the BA.4/5-dominant (hazard ratio, 0.71 [95% confidence interval, .63–79]) and the BQ-dominant (0.80 [.69–.94]) phases, but decreased risk was not found during the XBB-dominant phase (0.96 [.82–.1.12]). The estimated vaccine effectiveness was 29% (95% confidence interval, 21%–37%), 20% (6%–31%), and 4% (−12% to 18%), during the BA.4/5-, BQ-, and XBB-dominant phases, respectively. The risk of COVID-19 also increased with time since the most recent prior COVID-19 episode and with the number of vaccine doses previously received.’