Molnupiravir (Lageviro) antiviral treatment lead to the rapid accrual of hundreds of SARS-CoV-2 mutations; study demonstrates that Molnupiravir can ‘supercharge’ viral evolution potentially generating

by Paul Alexander

new variants and prolonging the pandemic; all patients treated with the drug accrued new mutations in the spike protein of the virus, including non-synonymous mutations that altered the amino acid seq

SOURCE:

https://www.medrxiv.org/content/10.1101/2022.12.21.22283811v1

 

All patients treated with the drug accrued new mutations in the spike protein of the virus, including non-synonymous mutations that altered the amino acid sequence. Our study demonstrates that this commonly used antiviral can ‘supercharge’ viral evolution in immunocompromised patients, potentially generating new variants and prolonging the pandemic.’

This, along with the mutations driven by the gene injection.