Perry et al.: "Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study"; Of the 95 studied patients, 70 had VITT & 25 did not; more death in VITT-linked CVT

by Paul Alexander

clinicians were asked to submit all cases in which COVID-19 vaccination preceded onset of cerebral venous thrombosis (CVT), regardless of the type of vaccine, interval between vaccine & onset of CVT

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01608-1/fulltext

‘Patients with VITT-associated cerebral venous thrombosis had more intracranial veins thrombosed (median three, IQR 2–4) than non-VITT patients (two, 2–3; p=0·041) and more frequently had extracranial thrombosis (31 [44%] of 70 patients) compared with non-VITT patients (one [4%] of 25 patients; p=0·0003). The primary outcome of death or dependency occurred more frequently in patients with VITT-associated cerebral venous thrombosis (33 [47%] of 70 patients) compared with the non-VITT control group (four [16%] of 25 patients; p=0·0061).’