Piernas et al.: "Associations of BMI with COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination in England: a population-based cohort study"
by Paul Alexander
association between BMI and COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination; first dose data is problematic
SOURCE:
What do we see? Yes, the study is busy in terms of the findings, looking at risk across different BMI body weights. They looked at the association between BMI and COVID-19 vaccine uptake, vaccine effectiveness, and risk of severe COVID-19 outcomes after vaccination by using a large, representative population-based cohort from England.’
But if we look inside, we see some interesting yet troubling data as it relates to the first, 2nd shot etc. despite it being across body weights. It appears on first blush that the vaccine confers protections etc. for heavier persons (vaccine for overweight or obese persons).
We also see higher deaths and hospital admissions after the first dose (Figure 2, page 577). Very pronounced for hospital admissions.
If we look at tables 5, 6 and 7, we see data in Table 7 jumping out as to risk of infection and hospitalization post vaccine (1st dose), using ‘no vaccine’ as the baseline for comparison. So look at the odds-ratios columns (ORs):
Table 7 focuses on infection risk:
